Absorption
After oral application, enrofloxacin, the active ingredient in Baytril, is readily absorbed from the duodenum and jejunum (1) and reaches high plasma concentrations within a short time. Absorption is best on an empty stomach, especially when given one hour before feeding of canned food (2). Resorption from parenteral injection sites is nearly complete (1). In general, bioavailability is excellent with similar plasma concentration curves after both oral and parenteral application.
References
| (1) |
Brown SA: Fluoroquinolones in animal health. J vet Pharmacol Therap 19: 1-14, 1996. |
| (2) |
Küng K, Wanner M: Einfluß zweier verschiedener Futter auf die Pharmacokinetik von oral appliziertem Baytril® (Enrofloxacin) beim Hund. Kleintierpraxis 38, 2: 95-102, 1993. | |
