Activity in presence of pus or cellular debris
In an environment where the degradative products of inflammation such as cellular debris or purulent exudate present an acidic, hyperosmolar and hypoxic environment, the activity of conventional antimicrobial drugs may be lowered or even totally impaired. The amphoteric and zwitterionic properties of the molecule make enrofloxacin highly lipid soluble. Therefore, it readily penetrates cellular debris, pus and inflammatory secretions and maintains its activity even against pathogens covered by a layer of inflammatory products.
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